Publications

Our Publications in PubMed
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  1. Cheng HS, Pérez-Cremades D, Zhuang R, Jamaiyar a, Wu W, Chen J, Tzani a, Stone L, Plutzky J, Ryan TE, Goodney PP, Creager MA, Sabatine MS, Bonaca MP, Feinberg MW. Impaired Angiogenesis in Diabetic Critical Limb Ischemia Is Mediated by a miR-130b/INHBA Signaling Axis. JCI Insight. 2023 May 22;8(10):e163041. PMID: 37097749.
  2. Cheng HS, Zhuang R, Pérez-Cremades D, Chen J, Jamaiyar a, Wu W, Sausen G, Tzani a, Plutzky J, Henao-Mejia J, Goodney PP, Creager MA, Sabatine MS, Bonaca MP, Feinberg MW. A miRNA/CXCR4 Signaling Axis Impairs Monopoiesis and Angiogenesis in Diabetic Critical Limb Ischemia. JCI Insight. 2023 Apr 10;8(7):e163360. PMID: 36821386; PMC10132154.
  3. Saini SK, Pérez-Cremades D, Cheng HS, Kosmac K, Peterson CA, Li L, Tian L, Dong G, Wu KK, Bouverat B, Wohlgemuth SE, Ryan T, Sufit RL, Ferrucci L, McDermott MM, Leeuwenburgh C, Feinberg MW. Dysregulated Genes, MicroRNAs, Biological Pathways, and Gastrocnemius Muscle Fiber Types Associated With Progression of Peripheral Artery Disease: A Preliminary Analysis. J Am Heart Assoc. 2022 Nov;11(21):e023085. PMID: 36300658; PMC9673627.
  4. Wara AK, Rawal S, Yang X, Pérez-Cremades D, Sachan M, Chen J, Feinberg MW. KLF10 Deficiency in CD4+ T Cells Promotes Atherosclerosis Progression by Altering Macrophage Dynamics. Atherosclerosis. 2022 Oct;359:27-41. PMID: 36174463.
  5. McCoy MG, Jamaiyar a, Sausen G, Cheng HS, Pérez-Cremades D, Zhuang R, Chen J, Goodney PP, Creager MA, Sabatine MS, Bonaca MP, Feinberg MW. MicroRNA-375 Repression of Kruppel-Like Factor 5 Improves Angiogenesis in Diabetic Critical Limb Ischemia. Angiogenesis. 2023 Feb;26(1):107-127. PMID: 36074222.
  6. Zhou H, Yang D, Cheng HS, McCoy MG, Pérez-Cremades D, Haemmig S, Wong D, Chen L, Feinberg MW. miR-181b Regulates Vascular Endothelial Aging by Modulating an MAP3K3 Signaling Pathway. FASEB J. 2022 Jun;36(6):e22353. PMID: 35593587; PMC9167053.
  7. Yang D, Haemmig S, Chen J, McCoy M, Cheng HS, Zhou H, Pérez-Cremades D, Cheng X, Sun X, Haneo-Mejia J, Vellarikkal SK, Gupta RM, Barrera v, Feinberg MW. Endothelial Cell-Specific Deletion of a microRNA Accelerates Atherosclerosis. Atherosclerosis. 2022 Jun;350:9-18. PMID: 35462240; PMC10165557.
  8. Zhuang R, Chen J, Cheng HS, Assa C, Jamaiyar a, Pandey AK, Pérez-Cremades D, Zhang B, Tzani a, Khyrul Wara a, Plutzky J, Barrera v, Bhetariya P, Mitchell RN, Liu Z, Feinberg MW. Perivascular Fibrosis Is Mediated by a KLF10-IL-9 Signaling Axis in CD4+ T Cells. Circ Res. 2022 May 27;130(11):1662-1681. PMID: 35440172; PMC9149118.
  9. Chen J, Zhuang R, Cheng HS, Jamaiyar a, Assa C, McCoy M, Rawal S, Pérez- Cremades D, Feinberg MW. Isolation and Culture of Murine Aortic Cells and RNA Isolation of Aortic Intima and Media: Rapid and Optimized Approaches for Atherosclerosis Research. Atherosclerosis. 2022 Apr;347:39-46. PMID: 35306416; PMC9007896.
  10. McCoy MG, Pérez-Cremades D, Belkin N, Peng W, Zhang B, Chen J, Sachan M, Wara AKMK, Zhuang R, Cheng HS, Feinberg MW. A miRNA Cassette Reprograms Smooth Muscle Cells Into Endothelial Cells. FASEB J. 2022 Apr;36(4):e22239. PMID: 35235229.
  11. Gross DA, Cheng HS, Zhuang R, McCoy MG, Pérez-Cremades D, Salyers Z, Wara AKMK, Haemmig S, Ryan TE, Feinberg MW. Deficiency of lncRNA SNHG12 Impairs Ischemic Limb Neovascularization by Altering an Endothelial Cell Cycle Pathway. JCI Insight. 2022 Jan 11;7(1):e150761. PMID: 34793334; PMC8765056.
  12. Ni H, Haemmig S, Deng Y, Chen J, Simion V, Yang D, Sukhova G, Shvartz E, Wara AKMK, Cheng HS, Pérez-Cremades D, Assa C, Sausen G, Zhuang R, Dai Q, Feinberg MW. A Smooth Muscle Cell-Enriched Long Noncoding RNA Regulates Cell Plasticity and Atherosclerosis by Interacting with Serum Response Factor. Arterioscler Thromb Vasc Biol. 2021 Sep;41(9):2399-2416. PMID: 34289702; PMC8387455.
  13. Sun X, Feinberg MW. Vascular Endothelial Senescence: Pathobiological Insights, Emerging Long Noncoding RNA Targets, Challenges and Therapeutic Opportunities. Front Physiol. 2021 Jun 16;12:693067. PMID: 34220553; PMC8242592.
  14. Haemmig S, Hashemi Gheinani A, Zaromytidou M, Siasos G, Coskun AU, Cormier MA, Gross DA, Wara AKMK, Antoniadis A, Sun X, Sukhova GK, Welt F, Andreou I, Whatling C, Gan LM, Wikström J, Edelman ER, Libby P, Stone PH, Feinberg MW. Novel Lesional Transcriptional Signature Separates Atherosclerosis With and Without Diabetes in Yorkshire Swine and Humans. Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1487-1503. PMID: 33567868; PMC7990701.
  15. Yang D, Haemmig S, Zhou H, Pérez-Cremades D, Sun X, Chen L, Li J, Haneo-Mejia J, Yang T, Hollan I, Feinberg MW. Methotrexate Attenuates Vascular Inflammation Through an Adenosine-microRNA-Dependent Pathway. Elife. 2021 Jan 8;10:e58064. PMID: 33416495; PMC7840179.
  16. Zhou H, Simion V, Pierce JB, Haemmig S, Chen AF, Feinberg MW. LncRNA-MAP3K4 Regulates Vascular Inflammation Through the p38 MAPK Signaling Pathway and Cis- Modulation of MAP3K4. FASEB J. 2021 Jan;35(1):e21133. PMID: 33184917.
  17. Wara AK, Wang S, Wu C, Fang F, Haemmig S, Weber BN, Aydogan CO, Tesmenitsky Y, Aliakbarian H, Hawse JR, Subramaniam M, Zhao L, Sage PT, Tavakkoli A, Garza A, Lynch L, Banks AS, Feinberg MW. KLF10 Deficiency in CD4<sup>+</sup> T Cells Triggers Obesity, Insulin Resistance, and Fatty Liver. Cell Rep. 2020 Dec 29;33(13):108550. PMID: 33378664; PMC7816773.
  18. Simion V, Zhou H, Haemmig S, Pierce JB, Mendes S, Tesmenitsky Y, Pérez- Cremades D, Lee JF, Chen AF, Ronda N, Papotti B, Marto JA, Feinberg MW. A Macrophage-Specific lncRNA Regulates Apoptosis and Atherosclerosis by Tethering HuR in the Nucleus. Nat Commun. 2020 Dec 1;11(1):6135. PMID: 33262333; PMC7708640.
  19. Simion V, Zhou H, Pierce JB, Yang D, Haemmig S, Tesmenitsky Y, Sukhova G, Stone PH, Libby P, Feinberg MW. LncRNA VINAS Regulates Atherosclerosis by Modulating NF-κB and MAPK Signaling. JCI Insight. 2020 Nov 5;5(21):e140627. PMID: 33021969; PMC7710319.
  20. Pierce JB, Feinberg MW. Long Noncoding RNAs in Atherosclerosis and Vascular Injury: Pathobiology, Biomarkers, and Targets for Therapy. Arterioscler Thromb Vasc Biol. 2020 Sep;40(9):2002-17. PMID: 32698685; PMC7484026.
  21. Barnett JV, Beckman JA, Bonaca MP, Carnethon MR, Cassis LA, Creager MA, Daugherty A, Feinberg MW, Freiberg MS, Goodney PP, Greenland P, Leeuwenburgh C, LeMaire SA, McDermott MM, Sabatine MS, Shen YH, Wasserman DH, Webb NR, Wells QS. American Heart Association Vascular Disease Strategically Focused Research Network. Arterioscler Thromb Vasc Biol. 2020 Mar;40(3):e47-e54. PMID: 31969016; PMC7047580.
  22. Haemmig S, Yang D, Sun X, Das D, Glaffari S, Molinaro R, Chen L, Deng Y Freeman D, Moullan N Tesmenitsky Y, Wara AKM, Simion V, Shvartz E, Lee JF, Yang, T, Sukhova G, Marto JA, Stone PH, Lee WL, Auwerx J, Libby P, Feinberg MW. Long Noncoding RNA SNHG12 Integrates a DNA-PK–Mediated DNA Damage Response and Vascular Senescence. Sci Transl Med. 2020 Feb 19;12(531):eaaw1868. PMID: 32075942; PMC5890095.
  23. Icli B, Wu W, Ozdemir D, Li H, Cheng HS, Haemmig S, Liu X, Giatsidis G, Avci SN, Lee N, Guimaraes RB, Manica A, Marchini JF, Rynning SE, Risnes I, Hollan I, Croce K, Yang X, Orgill DP, Feinberg MW. MicroRNA-615-5p Regulates Angiogenesis and Tissue Repair by Targeting AKT/eNOS (Endothelial NO Synthase) Signaling in Endothelial Cells. Arterioscler Thromb Vasc Biol. 2019 Jul;39(7):1458-74. PMID: 31092013; PMC6594892.
  24. Ozdemir D, Feinberg MW. MicroRNAs in Diabetic Wound Healing: Pathophysiology and Therapeutic Opportunities. Trends Cardiovasc Med. 2019 Apr;29(3):131-7. Review. PMID: 30143275; PMC6368472.
  25. Haemmig S, Simion V, Feinberg MW. Long Non-Coding RNAs in Vascular Inflammation. Front Cardiovasc Med. 2018 Mar 14;5:22. PMID: 29662883; PMC5890095.
  26. Sun X, He S, Wara AKM, Icli B, Shvartz E, Tesmenitsky Y, Belkin N, Li D, Blackwell TS, Sukhova GK, Croce K, Feinberg MW. Systemic Delivery of microRNA-181b Inhibits Nuclear Factor-κB Activation, Vascular Inflammation, and Atherosclerosis in Apolipoprotein E-Deficient Mice. Circ Res. 2014 Jan 3;114(1):32-40. PMID: 24084690; PMC4051320.
  27. Sun X, Icli B, Wara AK, Belkin N, He S, Kobzik L, Hunninghake GM, Vera MP; MICU Registry, Blackwell TS, Baron RM, Feinberg MW. MicroRNA-181b Regulates NF-κB-Mediated Vascular Inflammation. J Clin Invest. 2012 Jun;122(6):1973-90. PMID: 22622040; PMC3366408.
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